Saccharomyces cerevisiae Reference Assembly Panel Database (ScRAPdb)
Saccharomyces cerevisiae Reference Assembly Panel Database (ScRAPdb)
A searchable table of the S. cerevisiae pangenome ORFs defined in Peter et al. (2018) Nature (LINK) is provided below. The listed core/accessory classification and origin assignment are based on the original study. Click on the PanORF ID to find out the detailed presence/absence pattern of the corresponding pangenome ORF in both ScRAPdb and the 1002ScGP strain collections (which were recalculated by ScRAPdb).
| PanORF ID | SGD systematic Name | SGD standard name | Alias | Description | Type | Origin assignment | Mostly likely origin species | NCBI megablast hit |
|---|---|---|---|---|---|---|---|---|
| 7808-YPR190C | YPR190C | RPC82 | DNA-directed RNA polymerase III subunit C82|RPC80|RPC3 | RNA polymerase III subunit C82 | Core | NA | NA | NA |
| 7809-YPR191W | YPR191W | QCR2 | ubiquinol--cytochrome-c reductase subunit 2|UCR2|COR2 | Subunit 2 of ubiquinol cytochrome-c reductase (Complex III); Complex III is a component of the mitochondrial inner membrane electron transport chain; phosphorylated; transcription is regulated by Hap1p, Hap2p/Hap3p, and heme | Core | NA | NA | NA |
| 7810-YPR192W | YPR192W | AQY1 | NA | Spore-specific water channel; mediates the transport of water across cell membranes, developmentally controlled; may play a role in spore maturation, probably by allowing water outflow, may be involved in freeze tolerance | Accessory | Ancestral | NA | NA |
| 7811-YPR193C | YPR193C | HPA2 | histone acetyltransferase|KAT10 | Tetrameric histone acetyltransferase; has similarity to Gcn5p, Hat1p, Elp3p, and Hpa3p; acetylates histones H3 and H4 in vitro and exhibits autoacetylation activity; also acetylates polyamines | Core | NA | NA | NA |
| 7812-YPR194C | YPR194C | OPT2 | NA | Oligopeptide transporter; localized to peroxisomes and affects glutathione redox homeostasis; also localizes to the plasma membrane (PM) and to the late Golgi, and has a role in maintenance of lipid asymmetry between the inner and outer leaflets of the PM; member of the OPT family, with potential orthologs in S. pombe and C. albicans; also plays a role in formation of mature vacuoles and in polarized cell growth | Core | NA | NA | NA |
| 7813-YPR195C | YPR195C | NA | NA | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data | Accessory | Ancestral | NA | NA |
| 7814-YPR196W | YPR196W | NA | putative maltose-responsive transcription factor | Putative maltose-responsive transcription factor | Accessory | Ancestral | NA | NA |
| 7815-YPR198W_NumOfGenes_2 | YPR198W | SGE1 | NOR1 | Plasma membrane multidrug transporter; member of the major facilitator superfamily; acts as an extrusion permease; partial multicopy suppressor of gal11 mutations | Accessory | Ancestral | NA | NA |
| 7816-YPR199C_NumOfGenes_2 | YPR199C | ARR1 | ACR1|YAP8 | Transcriptional activator of the basic leucine zipper (bZIP) family; required for transcription of genes involved in resistance to arsenic compounds; directly binds trivalent arsenic (As(III)) as does K. lactis ortholog, KIYAP8 | Accessory | Introgression | S. paradoxus | NA |
| 7817-YPR200C_NumOfGenes_2 | YPR200C | ARR2 | ACR2 | Arsenate reductase required for arsenate resistance; converts arsenate to arsenite which can then be exported from cells by Arr3p | Accessory | Ancestral | NA | NA |
| 7818-YPR201W_NumOfGenes_2 | YPR201W | ARR3 | ACR3 | Plasma membrane metalloid/H+ antiporter; member of bile/arsenite/riboflavin transporter (BART) superfamily; transports arsenite and antimonite; required for resistance to arsenic compounds; transcription is activated by Arr1p in the presence of arsenite | Accessory | Introgression | S. paradoxus | NA |
| 7819-Q0010 | Q0010 | NA | ORF6 | Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF Q0017 | Accessory | Mithocondrial ORF | NA | NA |
| 7820-Q0017 | Q0017 | NA | ORF7 | Dubious open reading frame; unlikely to encode a protein, based on available experimental and comparative sequence data; partially overlaps the dubious ORF Q0010 | Accessory | Mithocondrial ORF | NA | NA |
| 7821-Q0045_NumOfGenes_9 | Q0045 | COX1 | cytochrome c oxidase subunit 1|OXI3 | Subunit I of cytochrome c oxidase (Complex IV); Complex IV is the terminal member of the mitochondrial inner membrane electron transport chain; one of three mitochondrially-encoded subunits | Accessory | Mithocondrial ORF | NA | NA |
| 7822-Q0080 | Q0080 | ATP8 | F1F0 ATP synthase subunit 8|AAP1 | Subunit 8 of the F0 sector of mitochondrial F1F0 ATP synthase; encoded on the mitochondrial genome; ATP8 and ATP6 mRNAs are not translated in the absence of the F1 sector of ATPase | Accessory | Mithocondrial ORF | NA | NA |