Saccharomyces cerevisiae Reference Assembly Panel Database (ScRAPdb)
Saccharomyces cerevisiae Reference Assembly Panel Database (ScRAPdb)
A searchable table of the S. cerevisiae pangenome ORFs defined in Peter et al. (2018) Nature (LINK) is provided below. The listed core/accessory classification and origin assignment are based on the original study. Click on the PanORF ID to find out the detailed presence/absence pattern of the corresponding pangenome ORF in both ScRAPdb and the 1002ScGP strain collections (which were recalculated by ScRAPdb).
| PanORF ID | SGD systematic Name | SGD standard name | Alias | Description | Type | Origin assignment | Mostly likely origin species | NCBI megablast hit |
|---|---|---|---|---|---|---|---|---|
| 7253-YOR296W | YOR296W | NA | NA | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; expressed during copper starvation; YOR296W is not an essential gene | Core | NA | NA | NA |
| 7254-YOR297C | YOR297C | TIM18 | NA | Component of the mitochondrial TIM22 complex; involved in insertion of polytopic proteins into the inner membrane; may mediate assembly or stability of the complex | Core | NA | NA | NA |
| 7255-YOR298C-A | YOR298C-A | MBF1 | SUF13 | Transcriptional coactivator; bridges the DNA-binding region of Gcn4p and TATA-binding protein Spt15p; suppressor of frameshift mutations; protein abundance increases in response to DNA replication stress | Core | NA | NA | NA |
| 7256-YOR298W | YOR298W | MUM3 | NA | Protein of unknown function involved in outer spore wall organization; has similarity to the tafazzins superfamily of acyltransferases | Core | NA | NA | NA |
| 7257-YOR299W | YOR299W | BUD7 | exomer complex subunit | Member of the ChAPs family (Chs5p-Arf1p-binding proteins); members include Bch1p, Bch2p, Bud7p, and Chs6p; ChAPs family proteins form the exomer complex with Chs5p to mediate export of specific cargo proteins, including Chs3p, from the Golgi to the plasma membrane; BUD7 has a paralog, BCH1, that arose from the whole genome duplication | Core | NA | NA | NA |
| 7258-YOR300W | YOR300W | NA | HUF1 | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data; overlaps with verified gene BUD7/YOR299W; mutation affects bipolar budding and bud site selection, though phenotype could be due to the mutation's effects on BUD7 | Core | NA | NA | NA |
| 7259-YOR301W | YOR301W | RAX1 | NA | Protein involved in bud site selection during bipolar budding; localization requires Rax2p; has similarity to members of the insulin-related peptide superfamily | Core | NA | NA | NA |
| 7260-YOR302W | YOR302W | NA | NA | CPA1 uORF; Arginine attenuator peptide, regulates translation of the CPA1 mRNA | Core | NA | NA | NA |
| 7261-YOR303W | YOR303W | CPA1 | carbamoyl-phosphate synthase (glutamine-hydrolyzing) CPA1 | Small subunit of carbamoyl phosphate synthetase; carbamoyl phosphate synthetase catalyzes a step in the synthesis of citrulline, an arginine precursor; translationally regulated by an attenuator peptide encoded by YOR302W within the CPA1 mRNA 5'-leader | Core | NA | NA | NA |
| 7262-YOR304C-A | YOR304C-A | BIL1 | EDO1 | Protein that binds Bud6p and has a role in actin cable assembly; involved in the Bnr1p-dependent pathway of cable assembly; localizes to bud tip and bud neck | Core | NA | NA | NA |
| 7263-YOR304W | YOR304W | ISW2 | DNA translocase | ATP-dependent DNA translocase involved in chromatin remodeling; ATPase component that, with Itc1p, forms a complex required for repression of a-specific genes, INO1, and early meiotic genes during mitotic growth; the Isw2 complex exhibits basal levels of chromatin binding throughout the genome as well as target-specific chromatin interactions; targeted by Ume6p- and Sua7p-dependent DNA looping to many loci genome-wide | Core | NA | NA | NA |
| 7264-YOR305W | YOR305W | RRG7 | NA | Protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the mitochondrion; deletion confers sensitivity to 4-(N-(S-glutathionylacetyl)amino) phenylarsenoxide (GSAO); YOR305W is not an essential gene | Core | NA | NA | NA |
| 7265-YOR306C | YOR306C | MCH5 | NA | Plasma membrane riboflavin transporter; facilitates the uptake of vitamin B2; required for FAD-dependent processes; sequence similarity to mammalian monocarboxylate permeases, however mutants are not deficient in monocarboxylate transport | Core | NA | NA | NA |
| 7266-YOR307C | YOR307C | SLY41 | NA | Protein involved in ER-to-Golgi transport | Core | NA | NA | NA |
| 7267-YOR308C | YOR308C | SNU66 | U4/U6-U5 snRNP complex subunit SNU66 | Component of the U4/U6.U5 snRNP complex; involved in pre-mRNA splicing via spliceosome; also required for pre-5S rRNA processing and may act in concert with Rnh70p; has homology to human SART-1 | Core | NA | NA | NA |