Saccharomyces cerevisiae Reference Assembly Panel Database (ScRAPdb)
Saccharomyces cerevisiae Reference Assembly Panel Database (ScRAPdb)
A searchable table of the S. cerevisiae pangenome ORFs defined in Peter et al. (2018) Nature (LINK) is provided below. The listed core/accessory classification and origin assignment are based on the original study. Click on the PanORF ID to find out the detailed presence/absence pattern of the corresponding pangenome ORF in both ScRAPdb and the 1002ScGP strain collections (which were recalculated by ScRAPdb).
| PanORF ID | SGD systematic Name | SGD standard name | Alias | Description | Type | Origin assignment | Mostly likely origin species | NCBI megablast hit |
|---|---|---|---|---|---|---|---|---|
| 6953-YOL155W-A | YOL155W-A | NA | NA | Putative protein of unknown function; identified by expression profiling and mass spectrometry | Accessory | Unknown | NA | NA |
| 6954-YOL156W_NumOfGenes_4 | YOL156W | HXT11 | hexose transporter HXT11|LGT3 | Hexose transporter; capable of transporting a broad range of substrates including: glucose, fructose, mannose and galactose; polyol transporter that supports the growth on and uptake of xylitol with low affinity when overexpressed in a strain deleted for hexose family members; nearly identical in sequence to Hxt9p; has similarity to major facilitator superfamily (MFS) transporters; involved in pleiotropic drug resistance | Accessory | Unknown | S. paradoxus | NA |
| 6955-YOL158C | YOL158C | ENB1 | ARN4 | Endosomal ferric enterobactin transporter; expressed under conditions of iron deprivation; member of the major facilitator superfamily; expression is regulated by Rcs1p and affected by chloroquine treatment | Accessory | Ancestral | NA | NA |
| 6956-YOL159C_NumOfGenes_2 | YOL159C | CSS3 | NA | Protein of unknown function, secreted when constitutively expressed; SWAT-GFP, seamless-GFP and mCherry fusion proteins localize to the cell periphery, SWAT-GFP fusion also localizes to the extracellular region, and mCherry fusion also localizes to the vacuole; deletion mutants are viable and have elevated levels of Ty1 retrotransposition and Ty1 cDNA | Accessory | Ancestral | NA | NA |
| 6957-YOL159C-A | YOL159C-A | NA | NA | Protein of unknown function; overexpression affects endocytic protein trafficking; identified by sequence comparison with hemiascomycetous yeast species | Accessory | Ancestral | NA | NA |
| 6958-YOL160W | YOL160W | NA | NA | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data | Accessory | Unknown | NA | NA |
| 6959-YOL162W | YOL162W | NA | NA | Putative protein of unknown function; member of the Dal5p subfamily of the major facilitator family | Accessory | Unknown | NA | NA |
| 6960-YOL163W | YOL163W | NA | NA | Putative protein of unknown function; member of the Dal5p subfamily of the major facilitator family | Accessory | Unknown | NA | NA |
| 6961-YOL164W | YOL164W | BDS1 | sulfuric ester hydrolase | Bacterially-derived sulfatase; required for use of alkyl- and aryl-sulfates as sulfur sources | Accessory | HGT | Lactobacillales | Lachancea thermotolerans CBS 6340 chr G |
| 6962-YOL164W-A | YOL164W-A | NA | NA | Putative protein of unknown function; identified by fungal homology and RT-PCR | Accessory | Unknown | NA | NA |
| 6963-YOL166C | YOL166C | NA | NA | Dubious open reading frame; unlikely to encode a functional protein, based on available experimental and comparative sequence data | Accessory | Unknown | NA | NA |
| 6964-YOL166W-A | YOL166W-A | NA | NA | Protein of unknown function; identified by gene-trapping, microarray-based expression analysis, and genome-wide homology searching | Accessory | Unknown | NA | NA |
| 6965-YOR001W | YOR001W | RRP6 | exosome nuclease subunit RRP6 | Nuclear exosome exonuclease component; has 3'-5' exonuclease activity that is regulated by Lrp1p; involved in RNA processing, maturation, surveillance, degradation, tethering, and export; role in sn/snoRNAs precursor degradation; forms a stable heterodimer with Lrp1p; has similarity to E. coli RNase D and to human PM-Sc1 100 (EXOSC10); mutant displays reduced transcription elongation in the G-less-based | Core | NA | NA | NA |
| 6966-YOR002W | YOR002W | ALG6 | dolichyl-P-Glc:Man(9)GlcNAc(2)-PP-dolichol alpha-1,3-glucosyltransferase | Alpha 1,3 glucosyltransferase; involved in transfer of oligosaccharides from dolichyl pyrophosphate to asparagine residues of proteins during N-linked protein glycosylation; C998T transition in human ortholog ALG6 causes carbohydrate-deficient glycoprotein syndrome type-Ic; wild-type human ortholog ALG6 can partially complement yeast alg6 mutant | Core | NA | NA | NA |
| 6967-YOR003W | YOR003W | YSP3 | putative subtilisin-like protease YSP3 | Putative precursor of the subtilisin-like protease III; SWAT-GFP and mCherry fusion proteins localize to the endoplasmic reticulum; YSP3 has a paralog, PRB1, that arose from the whole genome duplication | Core | NA | NA | NA |