Saccharomyces cerevisiae Reference Assembly Panel Database (ScRAPdb)
Saccharomyces cerevisiae Reference Assembly Panel Database (ScRAPdb)
A searchable table of the S. cerevisiae pangenome ORFs defined in Peter et al. (2018) Nature (LINK) is provided below. The listed core/accessory classification and origin assignment are based on the original study. Click on the PanORF ID to find out the detailed presence/absence pattern of the corresponding pangenome ORF in both ScRAPdb and the 1002ScGP strain collections (which were recalculated by ScRAPdb).
| PanORF ID | SGD systematic Name | SGD standard name | Alias | Description | Type | Origin assignment | Mostly likely origin species | NCBI megablast hit |
|---|---|---|---|---|---|---|---|---|
| 2363-YCR015C | YCR015C | CTO1 | NA | Protein required for cold tolerance; involved in phosphate uptake; YCR015C is not an essential gene | Core | NA | NA | NA |
| 2364-YCR016W | YCR016W | NA | NA | Putative protein of unknown function; green fluorescent protein (GFP)-fusion protein localizes to the nucleolus and nucleus; predicted to be involved in ribosome biogenesis | Core | NA | NA | NA |
| 2365-YCR017C | YCR017C | CWH43 | NA | GPI lipid remodelase; responsible for introducing ceramides into GPI anchors having a C26:0 fatty acid in sn-2 of the glycerol moiety; can also use lyso-GPI protein anchors and various base resistant lipids as substrates; contains 14-16 transmembrane segments and several putative glycosylation and phosphorylation sites; null mutation is synthetically lethal with pkc1 deletion | Core | NA | NA | NA |
| 2366-YCR018C | YCR018C | SRD1 | NA | Protein involved in the processing of pre-rRNA to mature rRNA; contains a C2/C2 zinc finger motif; srd1 mutation suppresses defects caused by the rrp1-1 mutation | Core | NA | NA | NA |
| 2367-YCR019W | YCR019W | MAK32 | NA | Protein necessary for stability of L-A dsRNA-containing particles | Core | NA | NA | NA |
| 2368-YCR020C | YCR020C | PET18 | HIT2 | Protein of unknown function; has weak similarity to proteins involved in thiamin metabolism; expression is induced in the absence of thiamin | Core | NA | NA | NA |
| 2369-YCR020C-A | YCR020C-A | MAK31 | NAA38|SMX1|LSM9 | Non-catalytic subunit of N-terminal acetyltransferase of the NatC type; required for replication of dsRNA virus; member of the Sm protein family | Core | NA | NA | NA |
| 2370-YCR020W-B | YCR020W-B | HTL1 | NA | Component of the RSC chromatin remodeling complex; RSC functions in transcriptional regulation and elongation, chromosome stability, and establishing sister chromatid cohesion; involved in telomere maintenance | Core | NA | NA | NA |
| 2371-YCR021C | YCR021C | HSP30 | YRO1 | Negative regulator of the H(+)-ATPase Pma1p; stress-responsive protein; hydrophobic plasma membrane localized; induced by heat shock, ethanol treatment, weak organic acid, glucose limitation, and entry into stationary phase | Core | NA | NA | NA |
| 2372-YCR022C | YCR022C | NA | NA | Putative protein of unknown function; conserved among S. cerevisiae strains; YCR022C is not an essential gene | Core | NA | NA | NA |
| 2373-YCR023C | YCR023C | NA | NA | Vacuolar membrane protein of unknown function; member of the multidrug resistance family; YCR023C is not an essential gene | Core | NA | NA | NA |
| 2374-YCR024C | YCR024C | SLM5 | asparagine--tRNA ligase SLM5 | Mitochondrial asparaginyl-tRNA synthetase | Core | NA | NA | NA |
| 2375-YCR024C-A | YCR024C-A | PMP1 | proteolipid ATPase | Regulatory subunit for the plasma membrane H(+)-ATPase Pma1p; small single-membrane span proteolipid; forms unique helix and positively charged cytoplasmic domain that is able to specifically segregate phosphatidylserines; PMP1 has a paralog, PMP2, that arose from the whole genome duplication | Core | NA | NA | NA |
| 2376-YCR024C-B | YCR024C-B | NA | NA | Putative protein of unknown function; identified by expression profiling and mass spectrometry | Core | NA | NA | NA |
| 2377-YCR025C | YCR025C | NA | NA | Putative protein of unknown function; conserved across S. cerevisiae strains; YCR025C is not an essential gene | Core | NA | NA | NA |